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‘Quad’ Comparable to Norvir-Reyataz Regimen in Phase III Study

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A study of Gilead Sciences’ “Quad” fixed-dose combination tablet containing the experimental integrase inhibitor elvitegravir and boosting agent cobicistat, along with tenofovir and emtricitabine, has met its primary objective—“non-inferiority” compared with the popular protease inhibitor?based regimen of Norvir (ritonavir)-boosted Reyataz (atazanavir) plus Truvada (tenofovir and emtricitabine)—according to data presented Thursday, March 8, at the 19th Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle.

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