A new African study of heterosexual HIV-serodiscordant couples—in which one partner is positive and the other is negative—confirms that viral load is the most important factor influencing the risk of transmitting the virus, according to data published in the February 1 issue of The Journal of Infectious Diseases. The findings also stress the importance of other transmission variables, including condom use, age, male circumcision status and the presence of other sexually transmitted infections (STIs).
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